Cyclooxygenase Inhibition in Ischemic Brain Injury
نویسندگان
چکیده
منابع مشابه
Cyclooxygenase inhibition in ischemic brain injury.
Neuroinflammation is one of the key pathological events involved in the progression of brain damage caused by cerebral ischemia. Metabolism of arachidonic acid through cyclooxygenase (COX) enzymes is known to be actively involved in the neuroinflammatory events leading to neuronal death after ischemia. Two isoforms of COX, termed COX-1 and COX-2, have been identified. Unlike COX-1, COX-2 expres...
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ژورنال
عنوان ژورنال: Current Pharmaceutical Design
سال: 2008
ISSN: 1381-6128
DOI: 10.2174/138161208784480216